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Rhodopsin in solvated lipid bilayer

This is work due to Paul Crozier and Mark Stevens at Sandia. It’s a study of the conformational properties of rhodopsin in both dark- and light-adapted states.

The movie shows the loop and helix dynamics the rhodopsin protein in a lipid bilayer (red) surrounded by water (blue) and counter-ions. The movie was made using VMD

Related publications

  • Molecular dynamics simulation of dark-adapted rhodopsin in an explicit membrane bilayer: Coupling between local retinal and larger scale conformational change, P. S. Crozier, M. J. Stevens, L. R. Forrest, and T. B. Woolf, J. Mol. Biol. 333, 493 (2003). doi:10.1016/j.jmb.2003.08.045