Probing eukaryotic cell mechanics via mesoscopic simulations
This work is by Kirill Lykov and Yasaman Nematbakhsh et al. at USI (Switzerland), NUS (Singapore), MIT (USA) to develop a new model for eukaryotic cells mechanics in a flow. The cell model incorporates a plasma membrane, nuclear envelope and internal cytoskeleton. It can be used to study cell deformations in microfluidic devices.
The movie shows simulations of two experiments: micropipette aspiration and flow in a microfluidic device. Mitsuba Renderer was used for the rendering.
Related publications
- Probing eukaryotic cell mechanics via mesoscopic simulations, K. Lykov, Y. Nematbakhsh, M. Shang, C. T. Lim, and I. V. Pivkin, PLOS Computational Biology 13, e1005726 (2017). doi:10.1371/journal.pcbi.1005726
