← back to the gallery

Probing eukaryotic cell mechanics via mesoscopic simulations

This work is by Kirill Lykov and Yasaman Nematbakhsh et al. at USI (Switzerland), NUS (Singapore), MIT (USA) to develop a new model for eukaryotic cells mechanics in a flow. The cell model incorporates a plasma membrane, nuclear envelope and internal cytoskeleton. It can be used to study cell deformations in microfluidic devices.

The movie shows simulations of two experiments: micropipette aspiration and flow in a microfluidic device. Mitsuba Renderer was used for the rendering.

Related publications

  • Probing eukaryotic cell mechanics via mesoscopic simulations, K. Lykov, Y. Nematbakhsh, M. Shang, C. T. Lim, and I. V. Pivkin, PLOS Computational Biology 13, e1005726 (2017). doi:10.1371/journal.pcbi.1005726